High-dose chemotherapy and stem cell transplantation for primary CNS lymphoma

Carole Soussain, Patrick Johnston, Gerald Illerhaus

Research output: Chapter in Book/Report/Conference proceedingChapter


The treatment of patients with CNS lymphoma has posed a challenge since this entity was first described. Several issues have complicated the management of these patients. First, it is important to define whether the lymphoma is confined to the CNS (primary CNS lymphoma, PCNSL) or whether there is co-existent or pre-existent systemic lymphoma (stage IV or secondary CNS lymphoma, respectively). Second, it is important to define the histological subtypes of lymphoma involving the CNS since multiple histologies are known to occur in the CNS and the treatment can vary depending on the histology.

Original languageEnglish (US)
Title of host publicationLymphoma and Leukemia of the Nervous System
PublisherSpringer New York
Number of pages14
ISBN (Electronic)9781441976680
ISBN (Print)9781441976673
StatePublished - Jan 1 2012

ASJC Scopus subject areas

  • General Medicine


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