Health Care Delivery Interventions for Hypertension Management in Underserved Populations in the United States: A Systematic Review

Maarya Pasha, La Princess C. Brewer, Susie Sennhauser, Mouaz Alsawas, M. Hassan Murad

Research output: Contribution to journalArticlepeer-review


The high prevalence of uncontrolled hypertension in underserved populations is a major cause of health disparities in the United States and requires innovative health care delivery interventions. We conducted a systematic review of randomized controlled trials and comparative observational studies examining the effectiveness of contemporary systems change and quality improvement interventions aimed at improving blood pressure (BP) control published from 2010 to 2020. We included studies evaluating multicomponent practice improvement interventions conducted in the United States in community health centers. We identified 26 studies including 48 187 patients with hypertension with a high proportion of racial/ethnic minorities, low socioeconomic status, and a high burden of chronic illness. Multicomponent interventions led to an average reduction of 5 to 10 mm Hg in systolic BP. Four studies demonstrated the effectiveness of integrating pharmacists into community health centers for BP management and reduced cardiovascular disparities for at-risk populations. Five studies demonstrated the effectiveness of integrating community health workers into care workflows leading to reduction in BP and high patient satisfaction. Five studies used the electronic medical record as a tool for population management and showed only modest reduction in BP. One study demonstrated the effectiveness of incentivizing clinics with higher payments for uninsured and Medicaid patients meeting performance criteria. Very few studies evaluated treatment complications or medications side effects. Multicomponent quality improvement interventions instituted in community health centers are effective in lowering BP. Several components of the interventions were identified as being associated with higher efficacy.

Original languageEnglish (US)
Pages (from-to)955-965
Number of pages11
Issue number4
StatePublished - Oct 1 2021


  • community health centers
  • implementation science
  • medically underserved area
  • minority groups
  • quality improvement

ASJC Scopus subject areas

  • Internal Medicine


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