Abstract
Three cases are reported of Hb S/Hb Lepore combination with very mild sickling manifestations. The presence of a nonα-chain variant with a high proportion of δ chain sequences, including 22 ala, appears to ameliorate sickle-cell disease. Efforts to increase the proportion of Hb A2 may be beneficial in sickle-cell disease.
Original language | English (US) |
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Pages (from-to) | 164-165 |
Number of pages | 2 |
Journal | American journal of hematology |
Volume | 54 |
Issue number | 2 |
DOIs | |
State | Published - 1997 |
Keywords
- Hb A
- Hb Lepore
- Hb S
- delta chain
- sickle-cell disease
ASJC Scopus subject areas
- Hematology