TY - GEN
T1 - Harmonization of detailed clinical models with clinical study data standards
AU - Jiang, Guoqian
AU - Evans, Julie
AU - Oniki, Tom
AU - Coyle, Joey
AU - Bain, Landen
AU - Huff, Stan
AU - Kush, Rebecca
AU - Chute, Christopher G.
PY - 2012
Y1 - 2012
N2 - Data sharing and integration between clinical research data management system (CDMS) and electronic health record (EHR) system remains a challenging issue. To deal with the challenge, there is emerging interest in utilizing the Detailed Clinical Modeling (DCM) approach across a variety of contexts. The Intermountain Healthcare Clinical Element Models (CEMs) have been adopted by the Office of the National Coordinator (ONC) awarded SHARPn project for normalizing patient data from the electronic medical records (EMRs). The objective of the present study is to describe our preliminary efforts on harmonization of the SHARPn CEMs with CDISC (Clinical Data Interchange Standards Consortium) clinical study data standards. We were focused on three generic domains: Demographics, Lab Tests and Medications. We performed a panel review on each data element extracted from the CDISC templates and SHARPn CEMs. We have identified a set of data elements that are common to the context of both clinical research and secondary use and discussed outstanding harmonization issues. We consider that the outcomes would be useful for defining new requirements for the DCM modeling community and ultimately facilitating the semantic interoperability between systems for both clinical research and secondary use.
AB - Data sharing and integration between clinical research data management system (CDMS) and electronic health record (EHR) system remains a challenging issue. To deal with the challenge, there is emerging interest in utilizing the Detailed Clinical Modeling (DCM) approach across a variety of contexts. The Intermountain Healthcare Clinical Element Models (CEMs) have been adopted by the Office of the National Coordinator (ONC) awarded SHARPn project for normalizing patient data from the electronic medical records (EMRs). The objective of the present study is to describe our preliminary efforts on harmonization of the SHARPn CEMs with CDISC (Clinical Data Interchange Standards Consortium) clinical study data standards. We were focused on three generic domains: Demographics, Lab Tests and Medications. We performed a panel review on each data element extracted from the CDISC templates and SHARPn CEMs. We have identified a set of data elements that are common to the context of both clinical research and secondary use and discussed outstanding harmonization issues. We consider that the outcomes would be useful for defining new requirements for the DCM modeling community and ultimately facilitating the semantic interoperability between systems for both clinical research and secondary use.
KW - Clinical research
KW - Data standards
KW - Detailed clinical models
KW - Electronic medical records
UR - http://www.scopus.com/inward/record.url?scp=84870435811&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84870435811&partnerID=8YFLogxK
U2 - 10.1145/2389672.2389678
DO - 10.1145/2389672.2389678
M3 - Conference contribution
AN - SCOPUS:84870435811
SN - 9781450317214
T3 - International Conference on Information and Knowledge Management, Proceedings
SP - 23
EP - 30
BT - MIX-HS'12 - Proceedings of the 2nd International Workshop on Managing Interoperability and Complexity in Health Systems, Co-located with CIKM 2012
T2 - 2nd International Workshop on Managing Interoperability and Complexity in Health Systems, MIX-HS 2012, Collocated with the 21st ACM International Conference on Information and Knowledge Management, CIKM 2012
Y2 - 29 October 2012 through 29 October 2012
ER -