Gut development on a full stomach

Research output: Contribution to journalArticlepeer-review


Mechanical forces are important for normal gastrointestinal development and function. Now, He et al. have discovered a population of Drosophila midgut epithelial enteroendocrine cell (EEC) precursors that express the mechanosensitive ion channel Piezo, which generates a calcium influx that drives EEC differentiation and proliferation in response to physiological mechanical stimuli.

Original languageEnglish (US)
Pages (from-to)394-395
Number of pages2
JournalNature Reviews Gastroenterology and Hepatology
Issue number7
StatePublished - Jul 1 2018

ASJC Scopus subject areas

  • Hepatology
  • Gastroenterology


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