Abstract
Since the sentinel discovery of long QT syndrome as a channelopathy in 1995, many significant strides have been made related to exposing the pathogenic mechanisms underlying sudden cardiac death. However, elucidating the most influential genetic and environmental determinants that underlie the variable penetrance and expressivity of the primary syndrome-associated mutation remains a daunting task.
Original language | English (US) |
---|---|
Pages (from-to) | 507-514 |
Number of pages | 8 |
Journal | Heart Failure Clinics |
Volume | 6 |
Issue number | 4 |
DOIs | |
State | Published - Oct 2010 |
Keywords
- Coronary artery disease
- Heart failure
- Sudden death
ASJC Scopus subject areas
- Cardiology and Cardiovascular Medicine