General parity between trio and pairwise breeding of laboratory mice in static caging

Ross M. Kedl; Lawrence J. Wysocki; William J. Janssen; Willi K. Born; Matthew D. Rosenbaum; Julia Granowski; Jennifer A. Kench; Derek L. Fong; Lisa A. Switzer; Margaret Cruse; Hua Huang; Claudia V. Jakubzick; Beata Kosmider; Katsuyuki Takeda; Thomas J. Stranova; Randal C. Klumm; Christine Delgado; Saigiridhar Tummala; Stijn De Langhe; John Cambier; Katherine Haskins; Laurel L. Lenz; Douglas Curran-Everett

doi:10.4049/jimmunol.1402306

General parity between trio and pairwise breeding of laboratory mice in static caging

Ross M. Kedl, Lawrence J. Wysocki, William J. Janssen, Willi K. Born, Matthew D. Rosenbaum, Julia Granowski, Jennifer A. Kench, Derek L. Fong, Lisa A. Switzer, Margaret Cruse, Hua Huang, Claudia V. Jakubzick, Beata Kosmider, Katsuyuki Takeda, Thomas J. Stranova, Randal C. Klumm, Christine Delgado, Saigiridhar Tummala, Stijn De Langhe, John CambierKatherine Haskins, Laurel L. Lenz, Douglas Curran-Everett

Pulmonary and Critical Care Medicine

Research output: Contribution to journal › Article › peer-review

Abstract

Changes made in the 8th edition of the Guide for the Care and Use of Laboratory Animals included new recommendations for the amount of space for breeding female mice. Adopting the new recommendations required, in essence, the elimination of trio breeding practices for all institutions. Both public opinion and published data did not readily support the new recommendations. In response, the National Jewish Health Institutional Animal Care and Use Committee established a program to directly compare the effects of breeding format on mouse pup survival and growth. Our study showed an overall parity between trio and pairwise breeding formats on the survival and growth of the litters, suggesting that the housing recommendations for breeding female mice as stated in the current Guide for the Care and Use of Laboratory Animals should be reconsidered.

Original language	English (US)
Pages (from-to)	4757-4760
Number of pages	4
Journal	Journal of Immunology
Volume	193
Issue number	10
DOIs	https://doi.org/10.4049/jimmunol.1402306
State	Published - Nov 15 2014

ASJC Scopus subject areas

Immunology and Allergy
Immunology

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Kedl, R. M., Wysocki, L. J., Janssen, W. J., Born, W. K., Rosenbaum, M. D., Granowski, J., Kench, J. A., Fong, D. L., Switzer, L. A., Cruse, M., Huang, H., Jakubzick, C. V., Kosmider, B., Takeda, K., Stranova, T. J., Klumm, R. C., Delgado, C., Tummala, S., De Langhe, S., ... Curran-Everett, D. (2014). General parity between trio and pairwise breeding of laboratory mice in static caging. Journal of Immunology, 193(10), 4757-4760. https://doi.org/10.4049/jimmunol.1402306

Kedl, RM, Wysocki, LJ, Janssen, WJ, Born, WK, Rosenbaum, MD, Granowski, J, Kench, JA, Fong, DL, Switzer, LA, Cruse, M, Huang, H, Jakubzick, CV, Kosmider, B, Takeda, K, Stranova, TJ, Klumm, RC, Delgado, C, Tummala, S, De Langhe, S, Cambier, J, Haskins, K, Lenz, LL & Curran-Everett, D 2014, 'General parity between trio and pairwise breeding of laboratory mice in static caging', Journal of Immunology, vol. 193, no. 10, pp. 4757-4760. https://doi.org/10.4049/jimmunol.1402306

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title = "General parity between trio and pairwise breeding of laboratory mice in static caging",

abstract = "Changes made in the 8th edition of the Guide for the Care and Use of Laboratory Animals included new recommendations for the amount of space for breeding female mice. Adopting the new recommendations required, in essence, the elimination of trio breeding practices for all institutions. Both public opinion and published data did not readily support the new recommendations. In response, the National Jewish Health Institutional Animal Care and Use Committee established a program to directly compare the effects of breeding format on mouse pup survival and growth. Our study showed an overall parity between trio and pairwise breeding formats on the survival and growth of the litters, suggesting that the housing recommendations for breeding female mice as stated in the current Guide for the Care and Use of Laboratory Animals should be reconsidered.",

author = "Kedl, {Ross M.} and Wysocki, {Lawrence J.} and Janssen, {William J.} and Born, {Willi K.} and Rosenbaum, {Matthew D.} and Julia Granowski and Kench, {Jennifer A.} and Fong, {Derek L.} and Switzer, {Lisa A.} and Margaret Cruse and Hua Huang and Jakubzick, {Claudia V.} and Beata Kosmider and Katsuyuki Takeda and Stranova, {Thomas J.} and Klumm, {Randal C.} and Christine Delgado and Saigiridhar Tummala and {De Langhe}, Stijn and John Cambier and Katherine Haskins and Lenz, {Laurel L.} and Douglas Curran-Everett",

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AU - Wysocki, Lawrence J.

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AU - Rosenbaum, Matthew D.

AU - Granowski, Julia

AU - Kench, Jennifer A.

AU - Fong, Derek L.

AU - Switzer, Lisa A.

AU - Cruse, Margaret

AU - Huang, Hua

AU - Jakubzick, Claudia V.

AU - Kosmider, Beata

AU - Takeda, Katsuyuki

AU - Stranova, Thomas J.

AU - Klumm, Randal C.

AU - Delgado, Christine

AU - Tummala, Saigiridhar

AU - De Langhe, Stijn

AU - Cambier, John

AU - Haskins, Katherine

AU - Lenz, Laurel L.

AU - Curran-Everett, Douglas

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General parity between trio and pairwise breeding of laboratory mice in static caging

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