Gene Regulation

P. W.L. Tai; K. Kapinas; J. B. Lian; Andre J van Wijnen; J. L. Stein; G. S. Stein

doi:10.1016/B978-0-12-374984-0.00602-1

Gene Regulation

P. W.L. Tai, K. Kapinas, J. B. Lian, Andre J van Wijnen, J. L. Stein, G. S. Stein

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

Gene regulation is the combined biological processes that contribute to the controlled expression of genetic information. These processes can be divided into two main mechanisms: (1) transcriptional regulation, which is controlled genetically by DNA-encoded regulatory machinery and epigenetically by non-DNA-encoded mechanisms, and (2) posttranscriptional regulation, which is controlled at the level of RNA stability through the action of RNA-binding proteins and microRNAs (miRNAs).

Original language	English (US)
Title of host publication	Brenner's Encyclopedia of Genetics
Subtitle of host publication	Second Edition
Publisher	Elsevier Inc.
Pages	216-220
Number of pages	5
ISBN (Electronic)	9780080961569
ISBN (Print)	9780123749840
DOIs	https://doi.org/10.1016/B978-0-12-374984-0.00602-1
State	Published - Feb 27 2013
Externally published	Yes

Keywords

Chromatin
Chromosome
DNA
Enhancer
Epigenetics
Methylation
MiRNA
MRNA
Nucleosome
Polyadenylation
Polymerase
Promoter
RNA
Transcription
Translation

ASJC Scopus subject areas

Agricultural and Biological Sciences(all)
Biochemistry, Genetics and Molecular Biology(all)
Medicine(all)

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10.1016/B978-0-12-374984-0.00602-1

Cite this

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title = "Gene Regulation",

abstract = "Gene regulation is the combined biological processes that contribute to the controlled expression of genetic information. These processes can be divided into two main mechanisms: (1) transcriptional regulation, which is controlled genetically by DNA-encoded regulatory machinery and epigenetically by non-DNA-encoded mechanisms, and (2) posttranscriptional regulation, which is controlled at the level of RNA stability through the action of RNA-binding proteins and microRNAs (miRNAs).",

keywords = "Chromatin, Chromosome, DNA, Enhancer, Epigenetics, Methylation, MiRNA, MRNA, Nucleosome, Polyadenylation, Polymerase, Promoter, RNA, Transcription, Translation",

author = "Tai, {P. W.L.} and K. Kapinas and Lian, {J. B.} and {van Wijnen}, {Andre J} and Stein, {J. L.} and Stein, {G. S.}",

year = "2013",

month = feb,

day = "27",

doi = "10.1016/B978-0-12-374984-0.00602-1",

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TY - CHAP

T1 - Gene Regulation

AU - Tai, P. W.L.

AU - Kapinas, K.

AU - Lian, J. B.

AU - van Wijnen, Andre J

AU - Stein, J. L.

AU - Stein, G. S.

PY - 2013/2/27

Y1 - 2013/2/27

N2 - Gene regulation is the combined biological processes that contribute to the controlled expression of genetic information. These processes can be divided into two main mechanisms: (1) transcriptional regulation, which is controlled genetically by DNA-encoded regulatory machinery and epigenetically by non-DNA-encoded mechanisms, and (2) posttranscriptional regulation, which is controlled at the level of RNA stability through the action of RNA-binding proteins and microRNAs (miRNAs).

AB - Gene regulation is the combined biological processes that contribute to the controlled expression of genetic information. These processes can be divided into two main mechanisms: (1) transcriptional regulation, which is controlled genetically by DNA-encoded regulatory machinery and epigenetically by non-DNA-encoded mechanisms, and (2) posttranscriptional regulation, which is controlled at the level of RNA stability through the action of RNA-binding proteins and microRNAs (miRNAs).

KW - Chromatin

KW - Chromosome

KW - DNA

KW - Enhancer

KW - Epigenetics

KW - Methylation

KW - MiRNA

KW - MRNA

KW - Nucleosome

KW - Polyadenylation

KW - Polymerase

KW - Promoter

KW - RNA

KW - Transcription

KW - Translation

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U2 - 10.1016/B978-0-12-374984-0.00602-1

DO - 10.1016/B978-0-12-374984-0.00602-1

M3 - Chapter

AN - SCOPUS:85043241533

SN - 9780123749840

SP - 216

EP - 220

BT - Brenner's Encyclopedia of Genetics

PB - Elsevier Inc.

ER -

Gene Regulation

Abstract

Keywords

ASJC Scopus subject areas

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