Gadolinium-DTPA- enhanced magnetic resonance imaging in intractable partial epilepsy

Gregory D. Cascino, Kathryn A. Hirschorn, Clifford R. Jack, Frank W. Sharbrough

Research output: Contribution to journalArticlepeer-review

25 Scopus citations


We performed magnetic resonance imaging (MRI), before and after the administration of gadolinium-DTPA (Gd-DTPA), in 23 patients with medically refractory partial epilepsy who subsequently had surgical treatment for their seizure disorder. In most patients, 61%, unenhanced and enhanced MRI studies were negative. In 26% the unenhanced image was positive, and the abnormality enhanced with Gd-DTPA. In 13% the unenhanced MR image was positive, but the abnormality did not enhance with Gd-DTPA. Gd-DTPA does not appear to increase the diagnostic yield of MRI in the presurgical evaluation of patients with partial epilepsy if the unenhanced MRIs are normal.

Original languageEnglish (US)
Pages (from-to)1115-1118
Number of pages4
Issue number8
StatePublished - Aug 1989

ASJC Scopus subject areas

  • Clinical Neurology


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