Frontal lobe epilepsy

Lily C. Wong-Kisiel; Gregory A. Worrell

doi:10.1007/978-3-030-59078-9_25

Frontal lobe epilepsy

Lily C. Wong-Kisiel, Gregory A. Worrell

Neurology

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

Frontal lobe seizures are characteristically brief and involving prominent motor behaviors, such as contralateral clonic or dystonic movements, symmetric or asymmetric tonic posture, and hyperkinetic motor behavior. Sleep-related hypermotor epilepsy is a distinct epilepsy syndrome, in which seizures are brief, hypermotor and occur in sleep, with frontal or extrafrontal localization. Genetic etiology can be seen in familial and idiopathic cases of sleep-related hypermotor epilepsy with pathogenic mutations found in CHRNA4, CHRNB2, CHRNA2, KCNT1, DEPDC5, or CRH genes. Frontal lobe epilepsy can be drug-resistant to antiseizure medication. Frontal lobe epilepsies account for 6-30% of all epilepsy surgeries. Favorable seizure outcome ranges from 20% to 78% depending on the series, with more variable long-term surgical outcome.

Original language	English (US)
Title of host publication	Epilepsy Case Studies
Subtitle of host publication	Pearls for Patient Care: Second Edition
Publisher	Springer International Publishing
Pages	139-144
Number of pages	6
ISBN (Electronic)	9783030590789
ISBN (Print)	9783030590772
DOIs	https://doi.org/10.1007/978-3-030-59078-9_25
State	Published - Dec 19 2020

Keywords

Asymmetric tonic and dystonic seizures
Epilepsy surgery
Hyperkinetic seizures
Psychogenic nonepileptic seizure
Sleep-related hypermotor epilepsy

ASJC Scopus subject areas

General Medicine

Access to Document

10.1007/978-3-030-59078-9_25

Cite this

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Frontal lobe epilepsy

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

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