Fertility (male and female) and menopause

Kathryn J. Ruddy, Ann H. Partridge

Research output: Contribution to journalReview articlepeer-review

30 Scopus citations


The impact of oncologic treatments on fertility and menopausal symptoms is often significant for patients with cancer. Surgery, radiation, and chemotherapy can all damage the reproductive organs or the hypothalamic pituitary axis that controls them, impairing fertility and causing hormonally mediated symptoms such as hot flashes. Understanding these risks and strategies to mitigate them may substantially improve cancer survivorship care. For both female and male patients who desire a future biologic child, there are a variety of fertility preservation techniques that should be considered. For cancer survivors who experience menopausal symptoms, lifestyle changes may be beneficial, and hormonal and nonhormonal pharmacologic agents are well proven to reduce symptom burden.

Original languageEnglish (US)
Pages (from-to)3705-3711
Number of pages7
JournalJournal of Clinical Oncology
Issue number30
StatePublished - Oct 20 2012

ASJC Scopus subject areas

  • Oncology
  • Cancer Research


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