Fashioning regulatory dendritic cells: What is currently in vogue?

T. Taner, A. W. Thomson

Research output: Contribution to journalReview articlepeer-review

3 Scopus citations


Dendritic cells (DCs) are uniquely well-equipped antigenpresenting cells with remarkable plasticity, whose differentiation and function can be manipulated in vitro and in vivo. With increased understanding of their immunoregulatory properties, strategies to enhance DC tolerogenicity have emerged. Carefully fashioned DCs, the result of biological, pharmacological or genetic modification, hold promise as new cell-based therapies of organ allograft rejection and autoimmune diseases.

Original languageEnglish (US)
Pages (from-to)78-82
Number of pages5
JournalCurrent Opinion in Molecular Therapeutics
Issue number1
StatePublished - Feb 2004


  • Autoimmunity
  • Dendritic cells
  • Immunotherapy
  • Tolerance
  • Transplantation

ASJC Scopus subject areas

  • Molecular Medicine
  • Molecular Biology
  • Genetics
  • Pharmacology
  • Drug Discovery
  • Genetics(clinical)


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