Factor VIII-Related Antigen in Kaposi's Sarcoma in Young Homosexual Men

Thomas J. Flotte; Virgil A. Hatcher; Alvin E. Friedman Kien

doi:10.1001/archderm.1984.01650380040007

Factor VIII-Related Antigen in Kaposi's Sarcoma in Young Homosexual Men

Thomas J. Flotte, Virgil A. Hatcher, Alvin E. Friedman Kien

Laboratory Medicine and Pathology

Research output: Contribution to journal › Article › peer-review

27 Scopus citations

Abstract

This study investigated the histogenesis of the Kaposi's sarcomas occurring in young homosexual men. Paraffin sections of seven tumors were stained for factor VIII-related antigen by the unlabeled peroxidase antiperoxidase method. Both the spindle cell component and the cells lining vascular channels contained factor VIII-related antigen, a marker for endothelial cells. Our study supports the hypothesis that both components of Kaposi's sarcoma are of endothelial cell origin.

Original language	English (US)
Pages (from-to)	180-182
Number of pages	3
Journal	Archives of Dermatology
Volume	120
Issue number	2
DOIs	https://doi.org/10.1001/archderm.1984.01650380040007
State	Published - Feb 1984

ASJC Scopus subject areas

Dermatology

Access to Document

10.1001/archderm.1984.01650380040007

Cite this

@article{5759a3becf8240ae8ead1d17006eb7dc,

title = "Factor VIII-Related Antigen in Kaposi's Sarcoma in Young Homosexual Men",

abstract = "This study investigated the histogenesis of the Kaposi's sarcomas occurring in young homosexual men. Paraffin sections of seven tumors were stained for factor VIII-related antigen by the unlabeled peroxidase antiperoxidase method. Both the spindle cell component and the cells lining vascular channels contained factor VIII-related antigen, a marker for endothelial cells. Our study supports the hypothesis that both components of Kaposi's sarcoma are of endothelial cell origin.",

author = "Flotte, {Thomas J.} and Hatcher, {Virgil A.} and {Friedman Kien}, {Alvin E.}",

year = "1984",

month = feb,

doi = "10.1001/archderm.1984.01650380040007",

language = "English (US)",

volume = "120",

pages = "180--182",

journal = "Archives of Dermatology",

issn = "0003-987X",

publisher = "American Medical Association",

number = "2",

}

TY - JOUR

T1 - Factor VIII-Related Antigen in Kaposi's Sarcoma in Young Homosexual Men

AU - Flotte, Thomas J.

AU - Hatcher, Virgil A.

AU - Friedman Kien, Alvin E.

PY - 1984/2

Y1 - 1984/2

N2 - This study investigated the histogenesis of the Kaposi's sarcomas occurring in young homosexual men. Paraffin sections of seven tumors were stained for factor VIII-related antigen by the unlabeled peroxidase antiperoxidase method. Both the spindle cell component and the cells lining vascular channels contained factor VIII-related antigen, a marker for endothelial cells. Our study supports the hypothesis that both components of Kaposi's sarcoma are of endothelial cell origin.

AB - This study investigated the histogenesis of the Kaposi's sarcomas occurring in young homosexual men. Paraffin sections of seven tumors were stained for factor VIII-related antigen by the unlabeled peroxidase antiperoxidase method. Both the spindle cell component and the cells lining vascular channels contained factor VIII-related antigen, a marker for endothelial cells. Our study supports the hypothesis that both components of Kaposi's sarcoma are of endothelial cell origin.

UR - http://www.scopus.com/inward/record.url?scp=0021359405&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0021359405&partnerID=8YFLogxK

U2 - 10.1001/archderm.1984.01650380040007

DO - 10.1001/archderm.1984.01650380040007

M3 - Article

C2 - 6421251

AN - SCOPUS:0021359405

SN - 0003-987X

VL - 120

SP - 180

EP - 182

JO - Archives of Dermatology

JF - Archives of Dermatology

IS - 2

ER -

Factor VIII-Related Antigen in Kaposi's Sarcoma in Young Homosexual Men

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this