Extra-hepatic hepatocellular carcinoma presenting as obstructive jaundice

J. A. Batsis, T. R. Halfdanarson, H. Pitot

Research output: Contribution to journalArticlepeer-review

2 Scopus citations


Hepatocellular carcinoma is a neoplasm with a uniformly poor prognosis. Risk factors for its development include chronic hepatitis B or C infection, haemochromatosis and α-1-antitrypsin deficiency, but individuals with any type of chronic liver disease are predisposed. The incidence is significantly higher in Asia and Africa although it has been noted to be increasing in the United States. We present a patient with notable atypical clinical features for hepatocellular carcinoma. The patient had neither predisposing risk factors nor a primary liver lesion causing obstructive jaundice. After multiple tissue specimens were obtained, the final pathological diagnosis was established. Hepatocellular carcinoma generally requires a surgical cure, but patients who are icteric often portend poorer prognoses. For those at high risk, screening may be indicated to identify early curative treatment.

Original languageEnglish (US)
Pages (from-to)768-771
Number of pages4
JournalDigestive and Liver Disease
Issue number10
StatePublished - Oct 2006


  • Hepatocellular carcinoma
  • Lymphadenopathy
  • Metastases
  • Obstructive jaundice

ASJC Scopus subject areas

  • Hepatology
  • Gastroenterology


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