TY - JOUR
T1 - Ex vivo coronary calcium volume quantification using a high-spatial-resolution clinical photon-counting-detector computed tomography
AU - Marsh, Jeffrey F.
AU - Vanmeter, Patrick D.
AU - Rajendran, Kishore
AU - Leng, Shuai
AU - McCollough, Cynthia H.
N1 - Publisher Copyright:
© 2023 SPIE. All rights reserved.
PY - 2023/7/1
Y1 - 2023/7/1
N2 - Coronary artery calcification (CAC) is an important indicator of coronary disease. Accurate volume quantification of CAC is challenging using computed tomography (CT) due to calcium blooming, which is a consequence of limited spatial resolution. Ex vivo coronary specimens were scanned on an ultra-high-resolution (UHR) clinical photon-counting detector (PCD) CT scanner, and the accuracy of CAC volume estimation was compared with a state-of-the-art conventional energyintegrating detector (EID) CT, a previous-generation investigational PCD-CT, and micro-CT.
AB - Coronary artery calcification (CAC) is an important indicator of coronary disease. Accurate volume quantification of CAC is challenging using computed tomography (CT) due to calcium blooming, which is a consequence of limited spatial resolution. Ex vivo coronary specimens were scanned on an ultra-high-resolution (UHR) clinical photon-counting detector (PCD) CT scanner, and the accuracy of CAC volume estimation was compared with a state-of-the-art conventional energyintegrating detector (EID) CT, a previous-generation investigational PCD-CT, and micro-CT.
KW - calcium quantification
KW - coronary artery disease
KW - coronary calcifications
KW - image domain denoising
KW - photon counting detector computed tomography
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U2 - 10.1117/1.JMI.10.4.043501
DO - 10.1117/1.JMI.10.4.043501
M3 - Article
AN - SCOPUS:85171695707
SN - 2329-4302
VL - 10
JO - Journal of Medical Imaging
JF - Journal of Medical Imaging
IS - 4
M1 - 043501
ER -