Evidence-based medicine has already adapted and is very much alive

Research output: Contribution to journalReview articlepeer-review


Greenhalgh et al 1 argue that the COVID-19 pandemic has uncovered a need for a shift in the evidence-based medicine (EBM) paradigm in which mechanistic evidence is also used as a complementary source for decision-making. Their justification is based on limitations of evidence hierarchies, which prioritise meta-analyses and randomised controlled trials (RCTs)1; and the urgency, threat and complexity of a pandemic. However, in defence of EBM, we present a counter argument.

Original languageEnglish (US)
Pages (from-to)261-262
Number of pages2
JournalBMJ evidence-based medicine
Issue number5
StatePublished - Jul 19 2022


  • Clinical Decision-Making
  • Evidence-Based Practice

ASJC Scopus subject areas

  • Medicine(all)


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