TY - JOUR
T1 - Evaluation of portal venous hypertension with cine phase-contrast MR flow measurements
T2 - High association of hyperdynamic portal flow with variceal hemorrhage
AU - Burkart, David J.
AU - Johnson, C. Daniel
AU - Ehman, Richard L.
AU - Weaver, Amy L.
AU - Ilstrup, Duane M.
PY - 1993/9
Y1 - 1993/9
N2 - Thirty-two patients with portal venous hypertension and endoscopically proved esophageal varices who were being evaluated for possible liver transplantation were studied with cine phase-contrast magnetic resonance (MR) imaging. Flow measurements in the main portal vein were obtained and associated with the presence of variceal hemorrhage within 2 years before the MR examination. Low (hypodynamic) flow was present in 22 patients, while high (hyperdynamic) flow was present in 10 patients. The presence of variceal hemorrhage was significantly associated with a high portal venous flow rate (P = .001), high variceal grade (P = .030), and Child class A or B (P = .003); however, only portal venous flow (P = .006) and variceal grade (P = .044) were found to be associated with variceal hemorrhage in a multiple logistic regression analysis. The portal venous flow rate was significantly higher among patients with Child class A or B disease compared with those with class C disease (median, 24.6 vs 8.0 mL/min·kg; P = .004).
AB - Thirty-two patients with portal venous hypertension and endoscopically proved esophageal varices who were being evaluated for possible liver transplantation were studied with cine phase-contrast magnetic resonance (MR) imaging. Flow measurements in the main portal vein were obtained and associated with the presence of variceal hemorrhage within 2 years before the MR examination. Low (hypodynamic) flow was present in 22 patients, while high (hyperdynamic) flow was present in 10 patients. The presence of variceal hemorrhage was significantly associated with a high portal venous flow rate (P = .001), high variceal grade (P = .030), and Child class A or B (P = .003); however, only portal venous flow (P = .006) and variceal grade (P = .044) were found to be associated with variceal hemorrhage in a multiple logistic regression analysis. The portal venous flow rate was significantly higher among patients with Child class A or B disease compared with those with class C disease (median, 24.6 vs 8.0 mL/min·kg; P = .004).
KW - Blood, flow dynamics, 957.711
KW - Esophagus, varices, 71.75
KW - Hypertension, portal, 957.711
KW - Liver, cirrhosis, 761.794
KW - Magnetic resonance (MR), phase imaging, 957.129416, 957.12944
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U2 - 10.1148/radiology.188.3.8351326
DO - 10.1148/radiology.188.3.8351326
M3 - Review article
C2 - 8351326
AN - SCOPUS:0027265560
SN - 0033-8419
VL - 188
SP - 643
EP - 648
JO - Radiology
JF - Radiology
IS - 3
ER -