Esophageal Squamous Cell Carcinoma

Jianmin Tian, Kenneth K. Wang

Research output: Chapter in Book/Report/Conference proceedingChapter


Esophageal squamous cell carcinoma is the predominant type of esophageal cancer worldwide, and in the United States, it has disproportionately high incidence and mortality in certain subgroups with cigarette smoking, excessive alcohol drinking, and comorbidities. This is particularly true in minority populations, which highlights health care disparities. Specific agents have been implicated in the pathogenesis of these tumors in select populations as well, such as polycyclic aromatic hydrocarbons generated from cooking. In recent years, many new endoscopic and laboratory technologies have been developed to diagnose this cancer at an early stage, and new staging guidelines have been published. Although there has been a tendency to combine all esophageal carcinomas for treatment studies, there is emerging evidence that these morphologically distinct entities have important differences in their biologies and metastatic potential. Recent studies also shed light on the complex multidisciplinary treatments for squamous cell carcinoma. This edition first published 2013

Original languageEnglish (US)
Title of host publicationHandbook of Gastrointestinal Cancer
PublisherJohn Wiley and Sons
Number of pages24
ISBN (Print)9780470656242
StatePublished - Nov 15 2012


  • Chemoradiotherapy
  • Endoscopic mucosal resection
  • Endoscopic submucosal dissection
  • Esophageal squamous cell carcinoma
  • Esophagectomy

ASJC Scopus subject areas

  • Medicine(all)


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