TY - JOUR
T1 - Erosive arthropathy
T2 - Clinical variance in lupus erythematosus and associated with anti-CCP case series and review of the literature
AU - Martinez, Jose Bernardo
AU - Valero, Jenny Soraida
AU - Bautista, Alain J.
AU - Restrepo, Jose Felix
AU - Matteson, Eric L.
AU - Rondon, Frederico
AU - Iglesias-Gamarra, Antonio
PY - 2007/1/1
Y1 - 2007/1/1
N2 - Objective: To describe the occurrence of erosive arthropathy in systemic lupus erythematosus (SLE) and its relationship to anti-CCP antibodies. Methods: Retrospective medical record review of a case series of five female patients with SLE and erosive arthropathies. Results: The initial disease presentation in all patients was a polyarthritis. Anti-CCP antibodies were detected in 4 out of 5 (80%) patients, 2 of whom had a positive rheumatoid factor. Conclusion: Erosive arthritis was strongly associated with the presence of anti-CCP antibodies in these patients with SLE, who presented with polyarthritis. Anti-CCP in patients with SLE may be a marker of a more severe joint disease.
AB - Objective: To describe the occurrence of erosive arthropathy in systemic lupus erythematosus (SLE) and its relationship to anti-CCP antibodies. Methods: Retrospective medical record review of a case series of five female patients with SLE and erosive arthropathies. Results: The initial disease presentation in all patients was a polyarthritis. Anti-CCP antibodies were detected in 4 out of 5 (80%) patients, 2 of whom had a positive rheumatoid factor. Conclusion: Erosive arthritis was strongly associated with the presence of anti-CCP antibodies in these patients with SLE, who presented with polyarthritis. Anti-CCP in patients with SLE may be a marker of a more severe joint disease.
KW - Anti-CCP
KW - Erosive arthritis
KW - Rhupus
KW - Systemic lupus erythematosus
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M3 - Article
C2 - 17417990
AN - SCOPUS:33947573778
SN - 0392-856X
VL - 25
SP - 47
EP - 53
JO - Clinical and experimental rheumatology
JF - Clinical and experimental rheumatology
IS - 1
ER -