Enhanced Shear Wave Velocity Calculation in Glaucoma Patients using Adaptive Singular Value Filter and Deep Neural Network in Ultrasound Elastography

Ngoc Thang Bui, Arash Kazemi, John Chen, Nicholas B. Larson, Arthur J Sit, Xiaoming Zhang

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Objective: The purpose of this study was to develop an adaptive singular value decomposition filter (SVF) method for improving calculation of shear wave velocity (SWV) on two locations of cornea and sclera for patients with glaucoma. Methods: Three patients with glaucoma and three healthy controls were enrolled in this study. We employed two independents adaptive SVFs for two regions of interest (ROI) of cornea and sclera (SVF-ROI). The deep neural network (DNN) was used to select the high efficiency cutoff value for SVF-ROI of two ROIs of cornea and sclera for reducing the noise of B-mode imaging and SWV. Results: We observed a trend of improved SNR when considering SWV values using three methods (i.e., no filter, the SVF, and SVF-ROI) for both eyes at the sclera (13.9, 14.8, and 19.6, respectively) and cornea (4.32, 4.29, and 9.78, respectively). Conclusion: significant improvement in SNR of SWV were found between the eyes with glaucoma and healthy eyes. Significance: The SVF-ROI provides an innovative method to increase accuracy of the vibro-ultrasound technique for assessing patients with glaucoma.

Original languageEnglish (US)
Title of host publicationIUS 2023 - IEEE International Ultrasonics Symposium, Proceedings
PublisherIEEE Computer Society
ISBN (Electronic)9798350346459
DOIs
StatePublished - 2023
Event2023 IEEE International Ultrasonics Symposium, IUS 2023 - Montreal, Canada
Duration: Sep 3 2023Sep 8 2023

Publication series

NameIEEE International Ultrasonics Symposium, IUS
ISSN (Print)1948-5719
ISSN (Electronic)1948-5727

Conference

Conference2023 IEEE International Ultrasonics Symposium, IUS 2023
Country/TerritoryCanada
CityMontreal
Period9/3/239/8/23

Keywords

  • adaptive singular value filter
  • deep neural network
  • glaucoma
  • shear wave velocity

ASJC Scopus subject areas

  • Acoustics and Ultrasonics

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