Endothelial function and cerebrovascular disease: Implications for diagnosis and treatment

Ahmad A. Elesber, Piero O. Bonetti, Amir Lerman

Research output: Contribution to journalArticlepeer-review

1 Scopus citations


Cerebrovascular disease remains one of the most common causes of morbidity and mortality in the United States. There is strong evidence to implicate endothelial dysfunction in the initiation and progression of atherosclerosis and its complications. It is now well known that endothelial dysfunction represents a systemic syndrome involving multiple vascular beds, including the cerebral vasculature. Currently, no gold standard treatment for endothelial dysfunction exists. Nonetheless, several treatment strategies have been found to be helpful in improving endothelial function. A few of these strategies have been implicated in stroke risk reduction as well, adding another line of evidence to the relationship between endothelial function and cerebrovascular disease.

Original languageEnglish (US)
Pages (from-to)213-219
Number of pages7
JournalCurrent Treatment Options in Cardiovascular Medicine
Issue number3
StatePublished - Jun 2006

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine


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