Elimination of spurious absent sweat response in QSWEAT recordings

Jeanne Corfits, Wolfgang Singer, Paola Sandroni, Robert D. Fealey, Elizabeth A. Coon, Eduardo E. Benarroch, Sarah E. Berini, Michelle L. Mauermann, David M. Sletten, Jeremy K. Cutsforth-Gregory, James D. Schmelzer, Phillip A. Low

Research output: Contribution to journalArticlepeer-review


Introduction: Forearm QSWEAT recordings are occasionally absent in females, likely due to high skin resistance. Methods: We identified consecutive subjects with no sudomotor abnormalities but absent/markedly reduced QSWEAT forearm volume, and repeated QSWEAT at the same site after gentle abrasion. Results: QSWEAT volumes were absent for 4 subjects and markedly reduced for the other 4 (median 0.01, IQR 0–0.03). After gentle skin abrasion, repeat volumes were significantly higher for all subjects and became normal in 7 of 8 subjects. Discussion: Skin abrasion restores QSWEAT volumes in previously absent/markedly reduced site suggesting that skin preparation using abrasion is more effective.

Original languageEnglish (US)
Article number102589
JournalAutonomic Neuroscience: Basic and Clinical
StatePublished - Dec 2019


  • Abrasion
  • Autonomic
  • Recording
  • Skin
  • Sudomotor

ASJC Scopus subject areas

  • Endocrine and Autonomic Systems
  • Clinical Neurology
  • Cellular and Molecular Neuroscience


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