Efficacy of levodopa therapy on motor function after posteroventral pallidotomy for Parkinson's disease

Ryan J. Uitti; Robert E. Wharen; Margaret F. Turk

doi:10.1212/WNL.51.6.1755

Efficacy of levodopa therapy on motor function after posteroventral pallidotomy for Parkinson's disease

Ryan J. Uitti, Robert E. Wharen, Margaret F. Turk

Research output: Contribution to journal › Article › peer-review

14 Scopus citations

Abstract

We evaluated motor function in 41 consecutive PD patients undergoing unilateral MRI/microelectrode-guided posteroventral pallidotomy to determine whether the motor effects of levodopa therapy change after surgery. Total Unified Parkinson's Disease Rating Scale motor 'off' and motor 'on' subscores all improved and the rapidity of action, magnitude, and duration of motor response to levodopa therapy were all maintained after pallidotomy.

Original language	English (US)
Pages (from-to)	1755-1757
Number of pages	3
Journal	Neurology
Volume	51
Issue number	6
DOIs	https://doi.org/10.1212/WNL.51.6.1755
State	Published - Dec 1998

ASJC Scopus subject areas

Clinical Neurology

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abstract = "We evaluated motor function in 41 consecutive PD patients undergoing unilateral MRI/microelectrode-guided posteroventral pallidotomy to determine whether the motor effects of levodopa therapy change after surgery. Total Unified Parkinson's Disease Rating Scale motor 'off' and motor 'on' subscores all improved and the rapidity of action, magnitude, and duration of motor response to levodopa therapy were all maintained after pallidotomy.",

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Efficacy of levodopa therapy on motor function after posteroventral pallidotomy for Parkinson's disease

Abstract

ASJC Scopus subject areas

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