Effects of treatment status and life quality on anxiety in MMT patients

Penghui Cao, Zhaohua Zhang, Jun Zhong, Shichao Xu, Qiaofang Huang, Ni Fan

Research output: Contribution to journalArticlepeer-review


Background: Anxiety, an important factor that affects the therapeutic effect and preservation rate of methadone maintenance treatment, has a high prevalence among MMT patients. This study aims to investigate the effects of treatment status and life quality on anxiety in MMT patients. Methods: One hundred and Seventy-seven methadone maintenance treatment users in Guangzhou, China were evaluated. The socio-demographic, duration and MMT-related characteristics were documented. Anxiety level and quality of life were evaluated by Beck Anxiety inventory (BAI) and the Quality of Life-Drug Addiction (QOL-DA) respectively. The correlation between different factors and BAI score was also analyzed. Results: The BAI total score and the QOL-DA score were 7.1±8.2, 163.5±21.4 respectively. 30.5% of the subjects showed mild to severe anxiety. Treatment interruption and QOL-DA score had strong correlations with the score of BAI, with correlation coefficients of 0.17 and − 0.08 respectively. Conclusions: Anxiety symptoms were commonly presented in MMT patients. Treatment interruption and quality of life are two major factors affecting anxiety of MMT patients.

Original languageEnglish (US)
Article number9
JournalSubstance Abuse: Treatment, Prevention, and Policy
Issue number1
StatePublished - Dec 2021


  • Anxiety
  • Methadone maintenance treatment
  • Quality of life

ASJC Scopus subject areas

  • Health Policy
  • Psychiatry and Mental health


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