Effects of a stereotactic headframe assembly on proton magnetic resonance spectroscopy

Norbert G. Campeau, Christopher P. Wood, Bradley J. Erickson, Clifford R. Jack, Joel P. Felmlee

Research output: Contribution to journalArticlepeer-review

2 Scopus citations


The effects of a magnetic resonance-compatible stereotactic headframe assembly on single voxel proton magnetic resonance spectroscopy (MRS) were investigated. Multiple stimulated echo acquisition mode (STEAM) spectra were obtained within a commercially available brain metabolite phantom placed within the headframe assembly (Leksell, Model G). All acquisition parameters were kept constant, except voxel location. Maximal distortion occurred for voxels acquired in the immediate vicinity of a headframe fixation pin, manifested by spectral broadening, changes in peak area and height and distortion of the baseline, rendering these acquisitions nondiagnostic. The range of this interaction was short, and a voxel acquired with nearest edge located 2.0 cm or greater from the fixation pin tip produced NAA/Cr, Cho/Cr and mI/Cr ratios differing by less than 7.5% from a spectrum obtained at the phantom center. The feasibility of performing single voxel MRS with a stereotactic headframe in place is demonstrated.

Original languageEnglish (US)
Pages (from-to)190-202
Number of pages13
JournalStereotactic and Functional Neurosurgery
Issue number4
StatePublished - Jan 1 1998


  • Imaging
  • Magnetic resonance
  • Spectroscopy
  • Stereotactic localization
  • Stereotactic techniques

ASJC Scopus subject areas

  • Surgery
  • Clinical Neurology


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