Effect of Sample Volume Location on Doppler-derived Transmitral Inflow Velocity Values

Zee P. Ding, Jae K. Oh, Allan L. Klein, A. Jamil Tajik

Research output: Contribution to journalArticlepeer-review

13 Scopus citations


In 25 patients with acute myocardial infarction and in 25 normal subjects, pulsed-wave Doppler echocardiography was performed in the apical four-chamber view with the sample volume first between the mitral leaflet tips and then at the mitral anulus. The early filling wave (E) and late filling wave (A) peak velocities measured from Doppler strip charts were significantly (p < 0.001) higher at the tips in both groups. E velocity increase was greater than A velocity increase, producing a significantly (p < 0.001) higher E/A velocity ratio at the tips than at the anulus. The deceleration time was longer at the tips than at the anulus (p < 0.001) in both groups. Therefore it is important to know sample volume location in the interpretation of mitral inflow velocity. It is critical to maintain the same sample volume location in serial assessments of left ventricular diastolic filling characteristics.

Original languageEnglish (US)
Pages (from-to)451-456
Number of pages6
JournalJournal of the American Society of Echocardiography
Issue number5
StatePublished - Jan 1 1991

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Cardiology and Cardiovascular Medicine


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