Edge-Enhancing Gradient-Echo MP2RAGE for Clinical Epilepsy Imaging at 7T

S. Tao; X. Zhou; E. Greco; V. Gupta; B. E. Freund; E. M. Westerhold; A. M. Feyissa; W. O. Tatum; S. Grewal; V. Patel; E. H. Middlebrooks

doi:10.3174/ajnr.A7782

Edge-Enhancing Gradient-Echo MP2RAGE for Clinical Epilepsy Imaging at 7T

S. Tao, X. Zhou, E. Greco, V. Gupta, B. E. Freund, E. M. Westerhold, A. M. Feyissa, W. O. Tatum, S. Grewal, V. Patel, E. H. Middlebrooks

Neurology

Research output: Contribution to journal › Article › peer-review

Abstract

The 3D edge-enhancing gradient-echo (EDGE) MR imaging sequence offers superior contrast-to-noise ratio in the detection of focal cortical dysplasia. EDGE could benefit from 7T MR imaging but also faces challenges such as image inhomogeneity and low acquisition efficiency. We propose an EDGE-MP2RAGE sequence that can provide both EDGE and T1-weighted contrast, simultaneously, improving data-acquisition efficiency. We demonstrate that with sequence optimization, EDGE images with sufficient uniformity and T1-weighted images with high gray-to-white matter contrast can be achieved.

Original language	English (US)
Pages (from-to)	268-270
Number of pages	3
Journal	American Journal of Neuroradiology
Volume	44
Issue number	3
DOIs	https://doi.org/10.3174/ajnr.A7782
State	Published - Mar 1 2023

ASJC Scopus subject areas

Radiology Nuclear Medicine and imaging
Clinical Neurology

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title = "Edge-Enhancing Gradient-Echo MP2RAGE for Clinical Epilepsy Imaging at 7T",

abstract = "The 3D edge-enhancing gradient-echo (EDGE) MR imaging sequence offers superior contrast-to-noise ratio in the detection of focal cortical dysplasia. EDGE could benefit from 7T MR imaging but also faces challenges such as image inhomogeneity and low acquisition efficiency. We propose an EDGE-MP2RAGE sequence that can provide both EDGE and T1-weighted contrast, simultaneously, improving data-acquisition efficiency. We demonstrate that with sequence optimization, EDGE images with sufficient uniformity and T1-weighted images with high gray-to-white matter contrast can be achieved.",

author = "S. Tao and X. Zhou and E. Greco and V. Gupta and Freund, {B. E.} and Westerhold, {E. M.} and Feyissa, {A. M.} and Tatum, {W. O.} and S. Grewal and V. Patel and Middlebrooks, {E. H.}",

year = "2023",

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doi = "10.3174/ajnr.A7782",

language = "English (US)",

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T1 - Edge-Enhancing Gradient-Echo MP2RAGE for Clinical Epilepsy Imaging at 7T

AU - Tao, S.

AU - Zhou, X.

AU - Greco, E.

AU - Gupta, V.

AU - Freund, B. E.

AU - Westerhold, E. M.

AU - Feyissa, A. M.

AU - Tatum, W. O.

AU - Grewal, S.

AU - Patel, V.

AU - Middlebrooks, E. H.

PY - 2023/3/1

Y1 - 2023/3/1

N2 - The 3D edge-enhancing gradient-echo (EDGE) MR imaging sequence offers superior contrast-to-noise ratio in the detection of focal cortical dysplasia. EDGE could benefit from 7T MR imaging but also faces challenges such as image inhomogeneity and low acquisition efficiency. We propose an EDGE-MP2RAGE sequence that can provide both EDGE and T1-weighted contrast, simultaneously, improving data-acquisition efficiency. We demonstrate that with sequence optimization, EDGE images with sufficient uniformity and T1-weighted images with high gray-to-white matter contrast can be achieved.

AB - The 3D edge-enhancing gradient-echo (EDGE) MR imaging sequence offers superior contrast-to-noise ratio in the detection of focal cortical dysplasia. EDGE could benefit from 7T MR imaging but also faces challenges such as image inhomogeneity and low acquisition efficiency. We propose an EDGE-MP2RAGE sequence that can provide both EDGE and T1-weighted contrast, simultaneously, improving data-acquisition efficiency. We demonstrate that with sequence optimization, EDGE images with sufficient uniformity and T1-weighted images with high gray-to-white matter contrast can be achieved.

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Edge-Enhancing Gradient-Echo MP2RAGE for Clinical Epilepsy Imaging at 7T

Abstract

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