Echocardiographic findings in pheochromocytoma

Clarence Shub, Luis Cueto-Garcia, Sheldon G. Sheps, Duane M. Ilstrup, A. Jamil Tajik

Research output: Contribution to journalArticlepeer-review

54 Scopus citations


M-mode and 2-dimensional echocardiography were used to study 26 consecutive, unselected patients with pheochromocytoma over a 3-year period. Only 1 patient had congestive heart failure; more than half had no cardiac symptoms or abnormalities. The most common (80% of patients) echocardiographic pattern was normal left ventricular (LV) mass with normal or even increased systolic performance. When LV mass was increased, LV systolic function was either normal or only borderline depressed in most of the patients. Patients with echocardiographic LV hypertrophy had symmetric thickening of ventricular walls; no case of asymmetric septal hypertrophy was found. There was no correlation between 24-hour urinary norepinephrine excretion and any of the echocardiographic variables studied. In some patients, increased LV wall thicknesses did not correlate with increased LV mass as calculated by the Woythaler echocardiographic method. Left atrial enlargement was not seen in any patient, including those with increased LV mass. The electrocardiogram and echocardiogram may be discordant: Electrocardiographic LV hypertrophy was seen in 6 patients, of whom 5 had normal echocardiographic LV mass. In patients with pheochromocytoma who have no cardiac symptoms or other clinical evidence of cardiac involvement, echocardiographic findings are usually normal.

Original languageEnglish (US)
Pages (from-to)971-975
Number of pages5
JournalThe American journal of cardiology
Issue number11
StatePublished - Apr 15 1986

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine


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