Dynamic gadolinium-enhanced rapid acquisition spin-echo MR imaging of the liver

Scott A. Mirowitz, Joseph K.T. Lee, Elsa Gutierrez, Jeffrey J. Brown, Jay P. Heiken, Steven S. Eilenberg

Research output: Contribution to journalArticlepeer-review

82 Scopus citations


Rapid acquisition spin-echo (RASE) magnetic resonance (MR) imaging allows for coverage of the entire liver with highly T1-weighted SE images during a single 23-second breath-holding period. The RASE sequence was implemented in conjunction with rapid intravenous injection of gadopentetate dimeglumine to enable performance of dynamic contrast material-enhanced MR imaging of the liver. Prospective evaluation of 24 patients with 62 liver lesions 1 cm or greater in diameter was performed. Images obtained with RASE were devoid of respiratory-related ghost artifacts or edge blurring. The dynamic contrast-enhanced RASE technique resulted in contrast-to-noise and contrast-to-artifact values and time efficiency measures significantly greater (P < .05) than those obtained with use of conventional T1- and T2-weighted pulse sequences, indicating a higher likelihood for lesion detectability. Lesion conspicuity was maximal during or immediately following bolus administration of gadopentetate dimeglumine, with lesions often becoming obscured at delayed postcontrast imaging.

Original languageEnglish (US)
Pages (from-to)371-376
Number of pages6
Issue number2
StatePublished - May 1991


  • Gadolinium
  • Liver neoplasms, MR studies, 761.1214, 761.31, 761.32, 761.33
  • Magnetic resonance (MR), contrast enhancement
  • Magnetic resonance (MR), pulse sequences
  • Magnetic resonance (MR), rapid imaging

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging


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