TY - JOUR
T1 - Dynamic aphasia as a variant of frontotemporal dementia
AU - Chandregowda, Adithya
AU - Clark, Heather M.
AU - Duffy, Joseph R.
AU - Machulda, Mary M.
AU - Lowe, Val J.
AU - Whitwell, Jennifer L.
AU - Josephs, Keith A.
N1 - Publisher Copyright:
© 2021 Lippincott Williams and Wilkins. All rights reserved.
PY - 2021/12/2
Y1 - 2021/12/2
N2 - We describe two individuals with progressive verbal difficulty who exhibited impairment of propositional language, with relatively well-preserved auditory comprehension, naming, and repetition -a profile that is consistent with dynamic aphasia. By providing a brief review of pertinent literature and the results from our neurologic, speech and language, neuropsychological, and neuroimaging testing, this report sheds light on the infrequently reported dynamic aphasia in the context of frontotemporal dementia. Our patients' insights into their verbal difficulty tend to support the notion that dynamic aphasia results from interference at the stage where thoughts are converted into verbal messages-that is, the thought-verbal interface.
AB - We describe two individuals with progressive verbal difficulty who exhibited impairment of propositional language, with relatively well-preserved auditory comprehension, naming, and repetition -a profile that is consistent with dynamic aphasia. By providing a brief review of pertinent literature and the results from our neurologic, speech and language, neuropsychological, and neuroimaging testing, this report sheds light on the infrequently reported dynamic aphasia in the context of frontotemporal dementia. Our patients' insights into their verbal difficulty tend to support the notion that dynamic aphasia results from interference at the stage where thoughts are converted into verbal messages-that is, the thought-verbal interface.
KW - Dynamic aphasia
KW - Frontotemporal dementia
KW - Left frontal lobe
KW - Primary progressive aphasia
KW - Propositional language
UR - http://www.scopus.com/inward/record.url?scp=85120550706&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85120550706&partnerID=8YFLogxK
U2 - 10.1097/WNN.0000000000000289
DO - 10.1097/WNN.0000000000000289
M3 - Article
C2 - 34851868
AN - SCOPUS:85120550706
SN - 1543-3633
VL - 34
SP - 303
EP - 318
JO - Cognitive and Behavioral Neurology
JF - Cognitive and Behavioral Neurology
IS - 4
ER -