Dual-source multienergy CT with triple or quadruple x-ray beams

Lifeng Yu, Liqiang Ren, Zhoubo Li, Shuai Leng, Cynthia H. McCollough

Research output: Contribution to journalArticlepeer-review

14 Scopus citations


Energy-resolved photon-counting-detector CT (PCD-CT) is promising for material decomposition with multiple contrast agents using two or more energy bins. However, corrections for nonidealities of PCDs are required, which are still active research topics. In addition, PCD-CT is also likely to have a very high cost due to the current lack of mass production capabilities. We proposed an alternative approach to perform multienergy CT (MECT), which is achieved by acquiring triple or quadruple x-ray beam measurements on a dual-source CT scanner. This strategy was based on a "twin-beam" design on a single-source scanner for dual-energy CT. Examples of beam filters and spectra for triple and quadruple x-ray beam were provided. Computer simulation studies were performed to evaluate the noise and accuracy of material decomposition for multiple contrast mixtures using both triple- and quadruple-beam configurations, compared with the performance on a PCD-CT platform. The results demonstrated that the image quality and dose efficiency of the triple-beam configuration in the proposed MECT technique were comparable to that in PCD-CT. The proposed technique can be readily implemented on a dual-source scanner, which may allow material decomposition of multiple contrast agents to be performed on clinical CT scanners with energy-integrating detectors.

Original languageEnglish (US)
Article number033502
JournalJournal of Medical Imaging
Issue number3
StatePublished - Jul 1 2018


  • basis material decomposition
  • dual-energy CT
  • dual-source CT
  • multienergy CT

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging


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