Dopamine agonist therapy for Parkinson disease and pathological gambling

Akiko Imamura, Ryan J. Uitti, Zbigniew K. Wszolek

Research output: Contribution to journalArticlepeer-review

38 Scopus citations


We report 6 patients with pathological gambling during pharmacologic treatment for Parkinson disease (PD). Four patients were treated with levodopa/carbidopa and dopamine agonist (DA), and 2 patients received DA monotherapy. We reviewed several published reports regarding pathological gambling and antiparkinsonian therapy and suggest that more advanced PD and antiparkinsonian combination therapy (e.g., levodopa/carbidopa and DA) increases the risk for development of pathological gambling behavior compared with monotherapy with either DA or levodopa/carbidopa.

Original languageEnglish (US)
Pages (from-to)506-508
Number of pages3
JournalParkinsonism and Related Disorders
Issue number8
StatePublished - Dec 2006


  • Dopamine agonist
  • Levodopa
  • Parkinson disease
  • Pathological gambling

ASJC Scopus subject areas

  • Neurology
  • Geriatrics and Gerontology
  • Clinical Neurology


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