TY - JOUR
T1 - Does area postrema syndrome occur in myelin oligodendrocyte glycoprotein-IgG-associated disorders (MOGAD)?
AU - Kunchok, Amy
AU - Krecke, Karl N.
AU - Flanagan, Eoin P.
AU - Jitprapaikulsan, Jiraporn
AU - Lopez-Chiriboga, A. Sebastian
AU - Chen, John J.
AU - Weinshenker, Brian G.
AU - Pittock, Sean J.
N1 - Publisher Copyright:
© American Academy of Neurology.
PY - 2020/1/14
Y1 - 2020/1/14
N2 - Myelin oligodendrocyte glycoprotein-IgG is a biomarker associated with CNS demyelinating diseases.1,2 MOGAD and aquaporin-4-IgG-positive neuromyelitis optica spectrum disorder (AQP4-IgG + NMOSD) have overlapping clinical features including optic neuritis and myelitis. However, there are several clinical and radiologic distinguishing features of MOGAD including lack of female predominance, higher incidence of acute disseminated encephalomyelitis (ADEM), higher proportion of bilateral optic neuritis, and T2-signal confined to gray matter and conus involvement in myelitis.1,3,4
AB - Myelin oligodendrocyte glycoprotein-IgG is a biomarker associated with CNS demyelinating diseases.1,2 MOGAD and aquaporin-4-IgG-positive neuromyelitis optica spectrum disorder (AQP4-IgG + NMOSD) have overlapping clinical features including optic neuritis and myelitis. However, there are several clinical and radiologic distinguishing features of MOGAD including lack of female predominance, higher incidence of acute disseminated encephalomyelitis (ADEM), higher proportion of bilateral optic neuritis, and T2-signal confined to gray matter and conus involvement in myelitis.1,3,4
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U2 - 10.1212/WNL.0000000000008786
DO - 10.1212/WNL.0000000000008786
M3 - Article
C2 - 31827002
AN - SCOPUS:85077800928
SN - 0028-3878
VL - 94
SP - 85
EP - 88
JO - Neurology
JF - Neurology
IS - 2
ER -