DNA Repair and Prostate Cancer: A Field Ripe for Harvest

Alan H. Bryce, Oliver Sartor, Johann de Bono

Research output: Contribution to journalEditorialpeer-review

5 Scopus citations


Recent data have revealed antitumor activity for four PARP inhibitors, two of which (olaparib and rucaparib) are approved by the US Food and Drug Administration for metastatic castrate-resistant prostate cancer with selected DNA repair defects. Additional clinical trials are in progress for talazoparib, veliparib, and niraparib. More progress can be anticipated in the near future.

Original languageEnglish (US)
Pages (from-to)486-488
Number of pages3
JournalEuropean urology
Issue number4
StatePublished - Oct 2020

ASJC Scopus subject areas

  • Urology


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