Disorders of coagulation

Aneel A. Ashrani, Nigel S. Key

Research output: Chapter in Book/Report/Conference proceedingChapter


Timely recognition and management of hemorrhage and thrombosis is fundamental to surgical critical care. Bleeding is a potential complication of almost every surgical procedure, and when appropriately anticipated, it can be managed with relative ease. The risk of venous thromboembolism is high postsurgery, but frequently can be reduced dramatically with appropriate prophylactic measures. This chapter reviews aspects of the pathophysiology of bleeding and thrombosis that are important to the critical care surgeon. By way of definition, the term “hemostasis” is used in reference to the normal physiologic (and usually desirable) blood clotting response to breaching of blood vessel integrity. Thrombosis is a term that refers to the pathologic (and therefore undesirable) response of the coagulation system to some form of insult, whether recognized or not.

Original languageEnglish (US)
Title of host publicationSurgical Critical Care, Second Edition
PublisherCRC Press
Number of pages22
ISBN (Electronic)9780824721480
ISBN (Print)9780824759117
StatePublished - Jan 1 2005

ASJC Scopus subject areas

  • General Medicine


Dive into the research topics of 'Disorders of coagulation'. Together they form a unique fingerprint.

Cite this