Four consecutive lymph node biopsies from one patient showed features typical of lymphocyte-predominant Hodgkin's disease. When the patient developed lymphocytosis of the peripheral blood and a staging bone marrow biopsy was found to have nodular lymphoid infiltrates atypical for Hodgkin's disease, the fourth node biopsy was performed in order to perform immunologic marker studies. A monoclonal cell population was identified and the lymph nodes were interpreted as chronic lymphocytic leukemia mimicking lymphocyte-predominant Hodgkin's disease. The diagnostic usefulness of immunologic marker studies is stressed.
|Number of pages
|American Journal of Surgical Pathology
|Published - 1981
ASJC Scopus subject areas
- Pathology and Forensic Medicine