Dietary calcium intake and rates of bone loss in women

B. L. Riggs, H. W. Wahner, L. J. Melton, L. S. Richelson, H. L. Judd, W. M. O'Fallon

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122 Scopus citations


We measured bone mineral density (BMD) at the midradius and lumbar spine in 106 normal women, ages 23-84 yr (61 were postmenopausal). Three to nine measurements (median, four) were made over 2.6 to 6.6 yr (mean, 4.1 yr). The correlation between calcium intake (range, 260-2,035 mg/de) and rate of change in BMD was not significant at the midradius (r = 0.06) or lumbar spine (r = 0.08), even after adjusting for age, menopausal status, and serum estrogen levels by multiple regression analysis. Women in the lower (mean, 501 mg/d) and in the upper (mean, 1,397 mg/d) quartiles of dietary intake had similar rates of change in BMD (%/yr [mean±SE], at midradius, -0.78±0.24 and -0.91±0.17 for lower and upper quartiles, respectively; at lumbar spine, -1.06±0.24 and -0.98±0.24). These data do not support the hypothesis that insufficient dietary calcium is a major cause of bone loss in women.

Original languageEnglish (US)
Pages (from-to)979-982
Number of pages4
JournalJournal of Clinical Investigation
Issue number4
StatePublished - 1987

ASJC Scopus subject areas

  • General Medicine


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