Diaphragm muscle adaptations in health and disease

Matthew J. Fogarty; Gary C. Sieck

doi:10.1016/j.ddmod.2019.10.002

Diaphragm muscle adaptations in health and disease

Matthew J. Fogarty, Gary C. Sieck

Physiology & Biomedical Engineering

Research output: Contribution to journal › Review article › peer-review

4 Scopus citations

Abstract

Breathing is achieved without thought despite being controlled by a complex neural network. The diaphragm is the predominant muscle responsible for force/pressure generation during breathing, but it is also involved in other non-ventilatory expulsive behaviors. This review considers alterations in diaphragm muscle fiber types and the neural control of the diaphragm across our lifespan and in various disease conditions.

Original language	English (US)
Pages (from-to)	43-52
Number of pages	10
Journal	Drug Discovery Today: Disease Models
Volume	29-30
DOIs	https://doi.org/10.1016/j.ddmod.2019.10.002
State	Published - Jun 1 2019

ASJC Scopus subject areas

Molecular Medicine
Drug Discovery

Access to Document

10.1016/j.ddmod.2019.10.002

Cite this

@article{6b4e368cf9654adab82ec787938f140f,

title = "Diaphragm muscle adaptations in health and disease",

abstract = "Breathing is achieved without thought despite being controlled by a complex neural network. The diaphragm is the predominant muscle responsible for force/pressure generation during breathing, but it is also involved in other non-ventilatory expulsive behaviors. This review considers alterations in diaphragm muscle fiber types and the neural control of the diaphragm across our lifespan and in various disease conditions.",

author = "Fogarty, {Matthew J.} and Sieck, {Gary C.}",

note = "Publisher Copyright: {\textcopyright} 2019 Elsevier Ltd",

year = "2019",

month = jun,

day = "1",

doi = "10.1016/j.ddmod.2019.10.002",

language = "English (US)",

volume = "29-30",

pages = "43--52",

journal = "Drug Discovery Today: Disease Models",

issn = "1740-6757",

publisher = "Elsevier Limited",

}

TY - JOUR

T1 - Diaphragm muscle adaptations in health and disease

AU - Fogarty, Matthew J.

AU - Sieck, Gary C.

PY - 2019/6/1

Y1 - 2019/6/1

N2 - Breathing is achieved without thought despite being controlled by a complex neural network. The diaphragm is the predominant muscle responsible for force/pressure generation during breathing, but it is also involved in other non-ventilatory expulsive behaviors. This review considers alterations in diaphragm muscle fiber types and the neural control of the diaphragm across our lifespan and in various disease conditions.

AB - Breathing is achieved without thought despite being controlled by a complex neural network. The diaphragm is the predominant muscle responsible for force/pressure generation during breathing, but it is also involved in other non-ventilatory expulsive behaviors. This review considers alterations in diaphragm muscle fiber types and the neural control of the diaphragm across our lifespan and in various disease conditions.

UR - http://www.scopus.com/inward/record.url?scp=85075867740&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85075867740&partnerID=8YFLogxK

U2 - 10.1016/j.ddmod.2019.10.002

DO - 10.1016/j.ddmod.2019.10.002

M3 - Review article

AN - SCOPUS:85075867740

SN - 1740-6757

VL - 29-30

SP - 43

EP - 52

JO - Drug Discovery Today: Disease Models

JF - Drug Discovery Today: Disease Models

ER -

Diaphragm muscle adaptations in health and disease

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this