Diagnostic dilemma in CNS Behçet's disease

Orla Ni Mhuircheartaigh; Christopher Hunt; Josephine Huang; Neeraj Kumar; Eric L. Matteson

doi:10.1136/bcr-2012-006610

Diagnostic dilemma in CNS Behçet's disease

Orla Ni Mhuircheartaigh, Christopher Hunt, Josephine Huang, Neeraj Kumar, Eric L. Matteson

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

A 23-year-old gentleman presented to the emergency department with new onset neurological dysfunction and painful oral and genital ulcers. Biopsies of the lesions noted non-speci fic inflammatory changes. MRI of the brain revealed a large mass-like lesion involving the pons, medulla, midbrain and surrounding cerebral tissue with T2 signal enhancement that was not amenable for biopsy. Both the ulcer biopsy results and the MRI findings could be attributed to either central nervous system (CNS) lymphoma or CNS Behçet's disease. A diagnosis of CNS Behçet's disease was thought to be most likely based on the clinical presentation and MRI findings. He was treated with high-dose immunosuppression and made a significant recovery.

Original language	English (US)
Journal	BMJ case reports
DOIs	https://doi.org/10.1136/bcr-2012-006610
State	Published - 2012

ASJC Scopus subject areas

Medicine(all)

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title = "Diagnostic dilemma in CNS Beh{\c c}et's disease",

abstract = "A 23-year-old gentleman presented to the emergency department with new onset neurological dysfunction and painful oral and genital ulcers. Biopsies of the lesions noted non-speci fic inflammatory changes. MRI of the brain revealed a large mass-like lesion involving the pons, medulla, midbrain and surrounding cerebral tissue with T2 signal enhancement that was not amenable for biopsy. Both the ulcer biopsy results and the MRI findings could be attributed to either central nervous system (CNS) lymphoma or CNS Beh{\c c}et's disease. A diagnosis of CNS Beh{\c c}et's disease was thought to be most likely based on the clinical presentation and MRI findings. He was treated with high-dose immunosuppression and made a significant recovery.",

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AU - Hunt, Christopher

AU - Huang, Josephine

AU - Kumar, Neeraj

AU - Matteson, Eric L.

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AB - A 23-year-old gentleman presented to the emergency department with new onset neurological dysfunction and painful oral and genital ulcers. Biopsies of the lesions noted non-speci fic inflammatory changes. MRI of the brain revealed a large mass-like lesion involving the pons, medulla, midbrain and surrounding cerebral tissue with T2 signal enhancement that was not amenable for biopsy. Both the ulcer biopsy results and the MRI findings could be attributed to either central nervous system (CNS) lymphoma or CNS Behçet's disease. A diagnosis of CNS Behçet's disease was thought to be most likely based on the clinical presentation and MRI findings. He was treated with high-dose immunosuppression and made a significant recovery.

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JO - BMJ case reports

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ER -

Diagnostic dilemma in CNS Behçet's disease

Abstract

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