Diagnostic dilemma in CNS Behçet's disease

Orla Ni Mhuircheartaigh, Christopher Hunt, Josephine Huang, Neeraj Kumar, Eric L. Matteson

Research output: Contribution to journalArticlepeer-review

1 Scopus citations


A 23-year-old gentleman presented to the emergency department with new onset neurological dysfunction and painful oral and genital ulcers. Biopsies of the lesions noted non-speci fic inflammatory changes. MRI of the brain revealed a large mass-like lesion involving the pons, medulla, midbrain and surrounding cerebral tissue with T2 signal enhancement that was not amenable for biopsy. Both the ulcer biopsy results and the MRI findings could be attributed to either central nervous system (CNS) lymphoma or CNS Behçet's disease. A diagnosis of CNS Behçet's disease was thought to be most likely based on the clinical presentation and MRI findings. He was treated with high-dose immunosuppression and made a significant recovery.

Original languageEnglish (US)
JournalBMJ case reports
StatePublished - 2012

ASJC Scopus subject areas

  • Medicine(all)


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