Abstract
The chronic autoimmune neuropathies are a diverse group of disorders, whose diagnosis and classification is based on the clinical presentations and results of ancillary tests. In chronic inflammatory demyelinating polyneuropathy, controlled therapeutic trials demonstrated efficacy for intravenous γ-globulins, corticosteroids, and plasmaphereis. In multifocal motor neuropathy, intravenous γ-globulins have been shown to be effective. In the other immune-mediated neuropathies, there are no reported controlled therapeutic trials, but efficacy has been reported for some treatments in non-controlled trials on case studies. Choice of therapy in individual cases is based on reported efficacy, as well as severity, progression, coexisting illness, predisposition to developing complications, and potential drug interactions.
Original language | English (US) |
---|---|
Pages (from-to) | 141-157 |
Number of pages | 17 |
Journal | Journal of clinical neuromuscular disease |
Volume | 7 |
Issue number | 3 |
DOIs | |
State | Published - Mar 2006 |
Keywords
- Autoimmune neuropathy
- Diagnosis
- Inflammatory neuropathy
- Peripheral neuropathy
- Therapy
- Vasculitic neuropathy
ASJC Scopus subject areas
- Neurology
- Clinical Neurology