Diagnosis and classification of ileal pouch disorders: consensus guidelines from the International Ileal Pouch Consortium

Bo Shen, Gursimran S. Kochhar, Revital Kariv, Xiuli Liu, Udayakumar Navaneethan, David T. Rubin, Raymond K. Cross, Akira Sugita, André D'Hoore, Jason Schairer, Francis A. Farraye, Ravi P. Kiran, Philip Fleshner, Joel Rosh, Samir A. Shah, Shannon Chang, Ellen Scherl, Darrell S. Pardi, David A. Schwartz, Paulo G. KotzeDavid H. Bruining, Sunanda V. Kane, Jessica Philpott, Bincy Abraham, Jonathan Segal, Rocio Sedano, Maia Kayal, Stuart Bentley-Hibbert, Dino Tarabar, Sandra El-Hachem, Priya Sehgal, James T. McCormick, Joseph A. Picoraro, Mark S. Silverberg, Charles N. Bernstein, William J. Sandborn, Séverine Vermeire

Research output: Contribution to journalReview articlepeer-review


Restorative proctocolectomy with ileal pouch–anal anastomosis is an option for most patients with ulcerative colitis or familial adenomatous polyposis who require colectomy. Although the construction of an ileal pouch substantially improves patients' health-related quality of life, the surgery is, directly or indirectly, associated with various structural, inflammatory, and functional adverse sequelae. Furthermore, the surgical procedure does not completely abolish the risk for neoplasia. Patients with ileal pouches often present with extraintestinal, systemic inflammatory conditions. The International Ileal Pouch Consortium was established to create this consensus document on the diagnosis and classification of ileal pouch disorders using available evidence and the panellists' expertise. In a given individual, the condition of the pouch can change over time. Therefore, close monitoring of the activity and progression of the disease is essential to make accurate modifications in the diagnosis and classification in a timely manner.

Original languageEnglish (US)
Pages (from-to)826-849
Number of pages24
JournalThe Lancet Gastroenterology and Hepatology
Issue number10
StatePublished - Oct 2021

ASJC Scopus subject areas

  • Hepatology
  • Gastroenterology


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