TY - JOUR
T1 - Diagnosing Lyme Disease
T2 - The Contribution of Serologic Testing
AU - DUFFY, JOSEPH
AU - MERTZ, LESTER E.
AU - WOBIG, GARY H.
AU - KATZMANN, JERRY A.
PY - 1988
Y1 - 1988
N2 - Lyme disease is a multisystem disorder caused by a tick-transmitted spirochete, Borrelia burgdorferi. The diagnosis is based on clinical findings in most patients, particularly those with erythema migrans or exposure to geographic locations endemic for the disease. Detection of a specific antibody to B. burgdorferi is a useful confirmatory test in many patients. In atypical cases, however, a positive test result can be pivotal for determining the diagnosis and can lead to institution of definitive treatment. Serologic testing should not be used indiscriminately to diagnose Lyme disease or as the sole basis for administration of antibiotic therapy.
AB - Lyme disease is a multisystem disorder caused by a tick-transmitted spirochete, Borrelia burgdorferi. The diagnosis is based on clinical findings in most patients, particularly those with erythema migrans or exposure to geographic locations endemic for the disease. Detection of a specific antibody to B. burgdorferi is a useful confirmatory test in many patients. In atypical cases, however, a positive test result can be pivotal for determining the diagnosis and can lead to institution of definitive treatment. Serologic testing should not be used indiscriminately to diagnose Lyme disease or as the sole basis for administration of antibiotic therapy.
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U2 - 10.1016/S0025-6196(12)65506-2
DO - 10.1016/S0025-6196(12)65506-2
M3 - Article
C2 - 3193820
AN - SCOPUS:0023760280
SN - 0025-6196
VL - 63
SP - 1116
EP - 1121
JO - Mayo Clinic proceedings
JF - Mayo Clinic proceedings
IS - 11
ER -