Abstract
The relationship between diabetes and pancreatic cancer is complex. Diabetes or impaired glucose tolerance is present in more than 2/3rd of pancreatic cancer patients. Epidemiological studies have consistently shown a modest increase in the risk of pancreatic cancer in type 2 diabetes, with an inverse relationship to duration of disease. Additionally, recent studies suggest that anti-diabetic medications may modulate the risk of pancreatic cancer in type 2 diabetes. Subjects >50 years of age with new onset diabetes are at higher risk of having pancreatic cancer. However, to screen new-onset diabetes for pancreatic cancer, additional markers are needed that can distinguish pancreatic cancer-associated diabetes from type 2 diabetes.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 331-345 |
| Number of pages | 15 |
| Journal | Minerva Gastroenterologica e Dietologica |
| Volume | 58 |
| Issue number | 4 |
| State | Published - Dec 2012 |
Keywords
- Diabetes mellitus
- Glucose intolerance
- Hyperinsulinemia
- Pancreatic cancer
ASJC Scopus subject areas
- Internal Medicine
- Endocrinology, Diabetes and Metabolism
- Nutrition and Dietetics
- Gastroenterology