Developmental trajectory of transmission speed in the human brain

Dorien van Blooijs; Max A. van den Boom; Jaap F. van der Aar; Geertjan M. Huiskamp; Giulio Castegnaro; Matteo Demuru; Willemiek J.E.M. Zweiphenning; Pieter van Eijsden; Kai J. Miller; Frans S.S. Leijten; Dora Hermes

doi:10.1038/s41593-023-01272-0

Developmental trajectory of transmission speed in the human brain

Dorien van Blooijs, Max A. van den Boom, Jaap F. van der Aar, Geertjan M. Huiskamp, Giulio Castegnaro, Matteo Demuru, Willemiek J.E.M. Zweiphenning, Pieter van Eijsden, Kai J. Miller, Frans S.S. Leijten, Dora Hermes

Physiology & Biomedical Engineering

Research output: Contribution to journal › Article › peer-review

Abstract

The structure of the human connectome develops from childhood throughout adolescence to middle age, but how these structural changes affect the speed of neuronal signaling is not well described. In 74 subjects, we measured the latency of cortico-cortical evoked responses across association and U-fibers and calculated their corresponding transmission speeds. Decreases in conduction delays until at least 30 years show that the speed of neuronal communication develops well into adulthood.

Original language	English (US)
Pages (from-to)	537-541
Number of pages	5
Journal	Nature Neuroscience
Volume	26
Issue number	4
DOIs	https://doi.org/10.1038/s41593-023-01272-0
State	Published - Apr 2023

ASJC Scopus subject areas

General Neuroscience

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10.1038/s41593-023-01272-0

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title = "Developmental trajectory of transmission speed in the human brain",

abstract = "The structure of the human connectome develops from childhood throughout adolescence to middle age, but how these structural changes affect the speed of neuronal signaling is not well described. In 74 subjects, we measured the latency of cortico-cortical evoked responses across association and U-fibers and calculated their corresponding transmission speeds. Decreases in conduction delays until at least 30 years show that the speed of neuronal communication develops well into adulthood.",

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AU - van Blooijs, Dorien

AU - van den Boom, Max A.

AU - van der Aar, Jaap F.

AU - Huiskamp, Geertjan M.

AU - Castegnaro, Giulio

AU - Demuru, Matteo

AU - Zweiphenning, Willemiek J.E.M.

AU - van Eijsden, Pieter

AU - Miller, Kai J.

AU - Leijten, Frans S.S.

AU - Hermes, Dora

PY - 2023/4

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Developmental trajectory of transmission speed in the human brain

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