Development of quality measures for the care of patients withgastroesophageal reflux disease

Rena Yadlapati, Andrew J. Gawron, Karl Bilimoria, Rajesh N. Keswani, Kerry B. Dunbar, Peter J. Kahrilas, Philip Katz, Joel Richter, Felice Schnoll-Sussman, Nathaniel Soper, Marcelo F. Vela, John E. Pandolfino

Research output: Contribution to journalArticlepeer-review

15 Scopus citations


Background & Aims: Gastroesophageal reflux disease (GERD) is a common and costly disorder. Symptoms attributed to GERD have a wide spectrum of presentations and complications that have led to complex diagnostic and management algorithms. As such, there is considerable variation in clinical approaches to GERD. In contrast to multiple published guidelines for the management of GERD, there are few validated GERD quality measures. The objective of this study was to use a well-described, formal methodology to develop valid, physician-led quality measures for all aspects of care for patients with GERD. Methods: Quality measures were identified from the literature, consensus guidelines, and GERD experts. Eight clinical experts ranked potential measures for validity on the basis of the RAND/Universityof California, Los Angeles Appropriateness Methodology. Results: Of the 52 proposed quality measures, 24 were rated as valid, and 1 new measure was developed. These valid measures were related to initial diagnosis and management (9), monitoring (3), further diagnostic testing (4), proton pump inhibitor refractory symptoms (2), symptoms of chest pain (1), erosive esophagitis (3), esophageal stricture or ring (1), and surgical therapy (2). Fifteen of these measures were ranked with the highest validity. Twenty-seven measures were determined to be equivocal; 89% of these were extracted from guidelines that were based on low or moderate level evidence. Conclusions: We used RAND/University of California, Los Angeles Appropriateness Methodology to develop quality measures for GERD care. By examining performance on these valid, formally developed quality measures, clinical practices and individual providers can assess their adherence with them and direct quality improvement efforts accordingly.

Original languageEnglish (US)
Pages (from-to)874-883.e2
JournalClinical Gastroenterology and Hepatology
Issue number5
StatePublished - May 1 2015


  • Gastroesophageal reflux disease (GERD)
  • Measure of quality of care
  • Proton pump inhibitor (PPI)
  • RAND/UCLA appropriateness methodology (RAM)

ASJC Scopus subject areas

  • Hepatology
  • Gastroenterology


Dive into the research topics of 'Development of quality measures for the care of patients withgastroesophageal reflux disease'. Together they form a unique fingerprint.

Cite this