Designer natriuretic peptides

Candace Y.W. Lee, Hsiao Lieu, John C. Burnett

Research output: Contribution to journalArticlepeer-review

17 Scopus citations


Designer natriuretic peptides (NPs) are novel hybrid peptides that are engineered from the native NPs through addition, deletion, or substitution of amino acid(s) with a goal toward optimization of pharmacological actions while minimizing undesirable effects. In this article, selected peptides that were designed in our laboratory are reviewed, and future directions for research and development of designer NPs are discussed.

Original languageEnglish (US)
Pages (from-to)18-21
Number of pages4
JournalJournal of Investigative Medicine
Issue number1
StatePublished - Jan 2009


  • Hybrid peptides
  • Natriuretic peptide
  • Renal function

ASJC Scopus subject areas

  • General Biochemistry, Genetics and Molecular Biology


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