Design and synthesis of novel pegylated 4-methylcoumarins

Mukesh K. Pandey; Rahul Tyagi; Shilpi Tomar; Jayant Kumar; Virinder S. Parmar; Arthur C. Watterson

doi:10.1080/10601320701608881

Design and synthesis of novel pegylated 4-methylcoumarins

Mukesh K. Pandey, Rahul Tyagi, Shilpi Tomar, Jayant Kumar, Virinder S. Parmar, Arthur C. Watterson

Radiology

Research output: Contribution to journal › Article › peer-review

13 Scopus citations

Abstract

Coumarins are well known for their antioxidant and anti-edema activities. Their antioxidant property gets enhanced with a methyl group at the C-4 position of the pyran ring. To increase the antioxidant potential and their hydrophilicity, a lipase (Novozyme 435) catalyzed copolymerization of 4-methylcoumarin diesters and polyethylene glycols (PEGs) has been carried out to give novel copolymers.

Original language	English (US)
Pages (from-to)	1293-1298
Number of pages	6
Journal	Journal of Macromolecular Science, Part A: Pure and Applied Chemistry
Volume	44
Issue number	12
DOIs	https://doi.org/10.1080/10601320701608881
State	Published - Dec 2007

Keywords

4-methylcoumarin
Antioxidant
Lipase
PEG

ASJC Scopus subject areas

Ceramics and Composites
Chemistry(all)
Polymers and Plastics
Materials Chemistry

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10.1080/10601320701608881

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title = "Design and synthesis of novel pegylated 4-methylcoumarins",

abstract = "Coumarins are well known for their antioxidant and anti-edema activities. Their antioxidant property gets enhanced with a methyl group at the C-4 position of the pyran ring. To increase the antioxidant potential and their hydrophilicity, a lipase (Novozyme 435) catalyzed copolymerization of 4-methylcoumarin diesters and polyethylene glycols (PEGs) has been carried out to give novel copolymers.",

keywords = "4-methylcoumarin, Antioxidant, Lipase, PEG",

author = "Pandey, {Mukesh K.} and Rahul Tyagi and Shilpi Tomar and Jayant Kumar and Parmar, {Virinder S.} and Watterson, {Arthur C.}",

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T1 - Design and synthesis of novel pegylated 4-methylcoumarins

AU - Pandey, Mukesh K.

AU - Tyagi, Rahul

AU - Tomar, Shilpi

AU - Kumar, Jayant

AU - Parmar, Virinder S.

AU - Watterson, Arthur C.

N1 - Funding Information: Authors are thankful to the University of Massachusetts Lowell for financial support.

PY - 2007/12

Y1 - 2007/12

N2 - Coumarins are well known for their antioxidant and anti-edema activities. Their antioxidant property gets enhanced with a methyl group at the C-4 position of the pyran ring. To increase the antioxidant potential and their hydrophilicity, a lipase (Novozyme 435) catalyzed copolymerization of 4-methylcoumarin diesters and polyethylene glycols (PEGs) has been carried out to give novel copolymers.

AB - Coumarins are well known for their antioxidant and anti-edema activities. Their antioxidant property gets enhanced with a methyl group at the C-4 position of the pyran ring. To increase the antioxidant potential and their hydrophilicity, a lipase (Novozyme 435) catalyzed copolymerization of 4-methylcoumarin diesters and polyethylene glycols (PEGs) has been carried out to give novel copolymers.

KW - 4-methylcoumarin

KW - Antioxidant

KW - Lipase

KW - PEG

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ER -

Design and synthesis of novel pegylated 4-methylcoumarins

Abstract

Keywords

ASJC Scopus subject areas

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