@inproceedings{0b1af3ff1d7948279861d6369ff2bffa,
title = "Deep Learning Prediction of Mild Cognitive Impairment using Electronic Health Records",
abstract = "About 44.4 million people have been diagnosed with dementia worldwide, and it is estimated that this number will be almost tripled by 2050. Predicting mild cognitive impairment (MCI), an intermediate state between normal cognition and dementia and an important risk factor for the development of dementia is crucial in aging populations. MCI is formally determined by health professionals through a comprehensive cognitive evaluation, together with a clinical examination, medical history and often the input of an informant (an individual that know the patient very well). However, this is not routinely performed in primary care visits, and could result in a significant delay in diagnosis. In this study, we used deep learning and machine learning techniques to predict the progression from cognitively unimpaired to MCI and also to analyze the potential for patient clustering using routinely-collected electronic health records (EHRs). Our analysis of EHRs indicates that temporal characteristics of patient data incorporated in a deep learning model provides increased power in predicting MCI.",
keywords = "Alzheimer's disease, deep learning, dementia, machine learning, mild cognitive impairment, recurrent neural networks",
author = "Sajjad Fouladvand and Mielke, {Michelle M.} and Maria Vassilaki and {St Sauver}, Jennifer and Petersen, {Ronald C.} and Sunghwan Sohn",
note = "Publisher Copyright: {\textcopyright} 2019 IEEE.; 2019 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2019 ; Conference date: 18-11-2019 Through 21-11-2019",
year = "2019",
month = nov,
doi = "10.1109/BIBM47256.2019.8982955",
language = "English (US)",
series = "Proceedings - 2019 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2019",
publisher = "Institute of Electrical and Electronics Engineers Inc.",
pages = "799--806",
editor = "Illhoi Yoo and Jinbo Bi and Hu, {Xiaohua Tony}",
booktitle = "Proceedings - 2019 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2019",
}