Deep brain stimulation: Preoperative issues

Anthony E. Lang, Jean Luc Houeto, Paul Krack, Cynthia Kubu, Kelly E. Lyons, Elena Moro, William Ondo, Rajesh Pahwa, Werner Poewe, Alexander I. Tröster, Ryan Uitti, Valerie Voon

Research output: Contribution to journalReview articlepeer-review

218 Scopus citations


Numerous factors need to be taken into account in deciding wether a patient with Parkinson's disease (PD) is a candidate for deep brain stimulation. Patient-related personal factors including age and the presence of other comorbid dis-orders need to be considered. Neuropsychological and neuropsychiatric concerns relate both to the presurgical status of the patient and to the potential for surgery to result in new problems postoperatively. A number of factors related to the underlying PD need to be considered, including the specific parkinsonian motor indications (e.g., tremor, bradykinesia, gait dysfunction), previous medical therapies, including benefit from current therapy and adverse effects, and past surgical treatments. Definable causes of Parkinsonism, particularly atypical Parkinsonisms, should be considered. Finally, methods of evaluating outcomes should be defined and formalized. This is a report from the Consensus on Deep Brain Stimulation for Parkinson's Disease, a project commissioned by the Congress of Neurological Surgeons and the Movement Disorder Society (MDS). The report has been endorsed by the Scientific Issues Committee of the MDS and the American Society of Stereotactic and Functional Neurosurgery. It outlines answers to a series of questions developed to address all aspects of deep brain stimulation preoperative decision-making.

Original languageEnglish (US)
Pages (from-to)S171-S196
JournalMovement Disorders
Issue numberSUPPL. 14
StatePublished - 2006


  • Contraindications
  • Deep brain stimulation
  • Indications
  • Parkinson's disease
  • Predictive factors

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology


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