Dedifferentiated liposarcoma of the esophagus: A case report and selected review of the literature

Christopher L. Brett, Daniel H. Miller, Liuyan Jiang, Herbert C. Wolfsen, Steven Attia, Lauren Hintenlang, Niveditha Jagadesh, Robert C. Miller

Research output: Contribution to journalReview articlepeer-review

2 Scopus citations


Soft tissue sarcomas of the esophagus represent an extremely rare cause of esophageal masses, and an even smaller proportion of these tumors represent dedifferentiated liposarcomas. We present a case of a 75-yearold gentleman presenting with dysphagia found to have a 5 cm pedunculated mass in the cervical esophagus, originating at the cricopharyngeus. This was found to have involvement limited to the superficial mucosa by endoscopic ultrasound, and the lesion was subsequently resected endoscopically. Pathology demonstrated an undifferentiated pleomorphic sarcoma later determined to represent dedifferentiated liposarcoma after fluorescence in situ hybridization analysis. The patient received no additional adjuvant therapy and remains disease free 20 months from the procedure. While treatment experience is limited, our case demonstrates that in selected patients, sustained local control can be obtained without radical resection.

Original languageEnglish (US)
Article number6791
Pages (from-to)201-202
Number of pages2
JournalRare Tumors
Issue number4
StatePublished - Dec 20 2016


  • Dedifferentiated liposarcoma
  • Esophageal mass
  • Surgical resection
  • Undifferentiated pleomorphic sarcoma

ASJC Scopus subject areas

  • Histology
  • Oncology


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